Recurrent sex cord tumor with annular tubules in Saint-Jérôme

Giant multilocular sex cord tumor with annular tubules associated with precocious puberty. The ones without PJS are usually unilateral and larger in size [ 28 ]. Giant multilocular sex cord tumor with annular tubules associated with precocious puberty.

Subsequent supervision should be followed every 3—6 months for 2 years and every 6—12 months after 2 years.

TWSL was the in-charge pathologist. We performed a unilateral salpingo-oophorectomy in view of minimal salvageable ovarian tissue. A retrospective study of 83 women with sex cord—stromal tumours 73 with granulosa cell tumour and 10 with Sertoli-Leydig cell tumourall diagnosed between andreported that survival was higher with age under 50, smaller tumour size, and absence of residual disease.

She had no axillary, pubic hair growth or rapid increase in height. Sparsely to intensely cellular proliferations of spindle cells with scanty cytoplasm are arranged in intersecting fascicles or occasionally a storiform pattern. References Qian Q. Author information Article notes Copyright and License information Disclaimer.

Gynecol Oncol Rep.

Recurrent sex cord tumor with annular tubules in Saint-Jérôme точно знаю

Rarely the tubules may have a gland-like appearance. Granulosa cell and Sertoli cell features granulosa cell-deeply indented nuclei, interdigitating plasma membranes joined by abundant desmosomes; Sertoli cell-variable Charcot-Bottcher filaments as cytoplasmic inclusions, Am J Clin Pathol ; Yolk sac tumor YST including polyvesicular vitelline variant and embryonal carcinoma.

Granulosa cells usually have scanty cytoplasm exceptions are noted below and pale, uniform, angular to oval, often grooved nuclei that are typically arranged haphazardly in relation to one another. The cut surfaces are typically solid and cystic with fluid recurrent sex cord tumor with annular tubules in Saint-Jérôme blood-filled cysts separated by solid, yellow to white, soft to firm tissue.

Systematic long-term follow-up data would be useful. One luteinized AGCT was associated with sclerosing peritonitis. Note the somewhat hyperchromatic nuclei with several mitotic figures.

  • Sex Cord—Stromal Tumors.
  • A seven-year-old girl who presented with precocious puberty was diagnosed with an estrogen-secreting right ovarian tumor. Right salpingo-oophorectomy with staging was performed by gynecologic oncologists.
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  • Sex cord—gonadal stromal tumour is a group of tumors derived from the stromal component of the ovary and testis , which comprises the granulosa , thecal cells and fibrocytes [1].
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Discussion The sex cord tumor with annular tubules SCTATs is a distinctive ovarian neoplasm, the predominant component of which has morphologic features intermediate between those of the granulosa cell tumor and those of the Sertoli cell tumor; focal differentiation into either granulosa cell or Sertoli cell tumor may occur.

The slides of original ovarian tumors in patients with recurrence were reviewed by pathologists in our hospital. Microscopically, circumscribed epithelial nests composed of ring-shaped tubules are seen with antipodal nuclear arrangement encircling hyaline globules, which is continuous with the basement membrane.

A year-old lady presented with abdominal pain and abdominal lump for the past one year.

Recurrent sex cord tumor with annular tubules in Saint-Jérôme

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  • Mar 10,  · Distinctive ovarian tumor associated with hyperestrinism (50%) 1/3 with tumor have Peutz-Jegher syndrome Peutz-Jegher syndrome: autosomal dominant with variable penetrance; patients have ovarian sex cord stromal tumors or tumorlets with annular tubules (almost all patients, usually bilateral, often with calcifications, tumorlets are benign); mucocutaneous melanin pigmentation (lips, . Nov 22,  · An ovarian sex cord tumor with annular tubules (SCTAT) is a tumor that grows from cells in the ovaries known as sex cord cells. As these cells grow, they form tube-like shapes in the tumor. SCTATs can develop in one or both ovaries, and may cause symptoms such as puberty at an exceptionally young age (precocious puberty), irregular menstrual cycles, or post-menopausal bleeding.
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  • Abstract: Sex cord tumor with annular tubules (SCTAT) is a rare special type of ovarian sex cord-stromal tumor, which has not achieved a standard treatment. Sex cord tumor with annular tubules (SCTATs) is a relatively rare ovarian neoplasm often having a syndromic association with Peutz-Jeghers.
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  • Oct 18,  · Slimane M., Gadria S., Hadidane M. Recurrence of sex cord tumor with annular tubules in young patient with Peutz-Jeghers syndrome. J. Case Rep. Images Oncol. ; – [Google Scholar] Nosov V., Park S., Rao J., Memarzadeh S. Non-Peutz-Jeghers syndrome associated ovarian sex cord stromal tumor with annular tubules: a case report. Fertil Author: L.T. Kwong, Y.F. Kwok, H.F. Hui, L.M. Wong, Tina W.S. Lau. Aug 04,  · Background. Sex cord tumour with annular tubules (SCTAT) is an uncommon, distinctive subtype of ovarian tumour. 1,2 First described by Scully in , accounts for less than 6% of sex cord stromal tumours 3, a third of which have an association with Peutz-Jeghers syndrome (PJS). Its rarity renders its clinical recognition difficult with diagnosis typically based on pathological examination Author: Dhanuja Senn, Miss Hisa Videira, Ben Haagsma, Mona El-Bahrawy, Thumuluru Kavitha Madhuri.
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  • Sex cord stromal tumor with annular tubules (SCTAT) is a distinctive, rare subtype of Keywords: Annular tubules, Peutz-Jegher syndrome, sex cord stromal tumor Other sites of tumor recurrence and metastasis include the retroperitoneum. Sex Cord Stromal Tumor with Annular Tubules: A Case Report, Selma Sengiz Erhan, Background: Sex cord tumor with annular tubules (SCTAT) is an uncommon radiotherapy are performed for local recurrence and distant metastasis [7].
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  • Sex Cord–Stromal Tumors These tumors (SCSTs), which account for ~5% of all primary ovarian tumors, are classified primarily on the basis of the constituent recognizable cell types (Table ): granulosa and theca cells, Sertoli cells, Leydig cells, and fibroblasts. Table Histologic classification of ovarian sex cord–stromal tumors Granulosa−stromal tumors Granulosa cell. Sex cord–gonadal stromal tumour is a group of tumors derived from the stromal component of the ovary and testis, which comprises the granulosa, thecal cells and contrast, the epithelial cells originate from the outer epithelial lining surrounding the gonad while the germ cell tumors arise from the precursor cells of the gametes, hence the name germ cell.
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  • Apr 12,  · 1. BMC Cancer. Apr 12; doi: /sy. Management and prognosis of patients with ovarian sex cord tumor with annular tubules: a retrospective study.
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